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pentobarbital will minimize the level or influence of exemestane by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. For patients getting exemestane that has a powerful CYP3A4 inducer the advised dose of exemestane is fifty mg every day after a food.Exemestane is metabolized with the liver enzyme CYP3A4. While the CYP3A4 in